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description de la société
Company Profile: Caring for the world, one person at a time, inspires and unites the people of Johnson & Johnson. We embrace innovation¿bringing ideas, products and services to life to advance the health and well-being of people around the world. We believe in collaboration which has led to breakthrough after breakthrough, from medical miracles that have changed lives, to the simple consumer products that make every day a little better. Our over 125,000 employees in 60 countries are united in a common mission: To help people everywhere live longer, healthier, happier lives. Provide a short description of your department & its main activities within J&J Drug Metabolism and Pharmacokinetics (DMPK) is a core scientific discipline within drug discovery and development as well as post¿marketing. It helps to design and select the most promising drug candidate and obtain advanced insights on the processes that control absorption, distribution, metabolism and excretion (ADME) of the final drug candidate in order to understand the pharmacokinetics, pharmacodynamics and safety of the novel drug in patients. The Analytical Sciences team provides the analytical support for the DMPK department. They perform analysis of in vitro and in vivo samples for end-to-end metabolite profiling and identification as well as quantification of drug candidates, metabolites and biomarkers. In the department of Analytical Sciences DMPK we currently have an internship position for a master student with background or interest in (analytical) chemistry (m/f).
description de la fonction
Job description: The intensity of the signals obtained by mass spectrometry is highly dependent on the chemical structure of the compound analysed. Therefore, only compounds for which an authentic standard is available can be quantified using mass spectrometry. In metabolism studies, drug metabolites are identified for which no standards are available. In this project we will evaluate a new tool developed at the University of Tartu in Estonia to predict the mass spectrometry response of compounds. We will evaluate the possibilities of the software and its accuracy to predict the relative abundance of drug metabolites.
Responsibilities and duties:
Processing of existing analytical data: - Evaluating new software tools - Setting up new methodologies to come to the most accurate results - Analyzing new samples and/or compounds to evaluate the methodology
Qualifications: - Master in chemistry, pharmaceutical sciences, industrial or civil engineering or equivalent - Background or interest in chemistry - Interest in working in a pharmaceutical R&D environment
Practical details: - Location: Janssen R&D, Beerse - Duration: 3 ¿ 9 months - Timeframe: as soon as possible
Requirement: The candidate must be a registered student for the entire course of the internship. Unfortunately, graduates that are currently not enrolled in a study program are not eligible for this internship. If you are interested in applying for this challenging internship, please send an e-mail to RA-RNDBE-InternBelg@ITS.JNJ.com, including your resume and a short motivation.